The most common types of brochures are bi-fold - which results in 4 panels, and tri-fold which results in six panels. As with all other design, it is important to keep in mind your audience, who are you trying to give information to with this brochure, this should largely impact how you design. Further, with brochures it is important to use graphics of imagery to draw people in, a brochure filled with text and nothing visual pleasing will not get picked up. So think of the audience and what style will draw that audience in. They are informational but they are also interesting.
Here are some examples of brochures that I really liked and that really grabbed my attention